Sterilization and acne treatment new darling | Quaternary ammonium salt-73
Release time:2025-08-06
Quaternium-73
Quaternium-73, also known as "PIONIN," is a broad-spectrum, highly effective bactericide widely used in products for treating acne, pimples, and blackheads.
Quaternium-73 has strong antibacterial activity, effectively killing bacteria, staphylococcus, and E. coli. It quickly clears acne, effectively inhibits Cutibacterium acnes, and is a nemesis to closed comedones. It's commonly found as an acne-clearing ingredient in Japanese over-the-counter (OTC) medications.
Understanding "Acne"
Acne (medically termed acne vulgaris) is a chronic inflammatory skin disease of the pilosebaceous unit, commonly affecting the face, chest, and back—areas with seborrhea. It is the eighth most prevalent disease globally, significantly impacting patients' appearance and mental health.
Acne is a common skin disease, prevalent among adolescents. Clinical manifestations include comedones, papules, pustules, and nodules, often accompanied by seborrhea.
It commonly appears on the face, especially on the forehead, nose, and chin, where oil secretion is abundant, and can also be found on the chest and back. Generally, in 15-16-year-old adolescents, hormones stimulate hair growth and sebaceous gland secretion, leading to pore blockage and the formation of comedones. Further infection results in acne. Sebaceous gland secretion is weak before age 10, peaks between 16 and 35, and weakens in old age; this explains its prevalence among young people.
The occurrence of acne is associated with androgen-induced excessive sebum secretion, abnormal keratinization of the pilosebaceous duct, proliferation of Cutibacterium acnes and other follicular microorganisms, inflammatory immune responses, and genetics. It is also influenced by endocrine factors, emotions, diet, improper skincare product use, and sun exposure.
Three Key Factors in Acne Formation
1. Excessive sebum (oil) secretion;
2. Pore blockage;
3. Bacterial infection;
The Key to Acne Treatment Lies in Bactericidal and Anti-inflammatory Actions
Bactericidal Action: Cutibacterium acnes is the sole causative agent of acne, and this bacterium is particularly difficult to kill, so ordinary bactericides may not be effective against it.
Quaternium-73 is especially recommended due to its unique "bactericidal" mechanism, resulting in extremely strong bactericidal and antibacterial activity.
1. Damages bacterial and fungal cell membranes, highly effective against Cutibacterium acnes;
2. Promotes intercellular degradation of bacteria, accelerating maturation.
Its primary mechanism of action targets bacterial cells, damaging their cell membranes and promoting intercellular degradation. This removes their protective layers, accelerating acne maturation, facilitating the outflow of secretions, and causing acne to disappear quickly.
It also effectively inhibits various types of bacteria and fungi; even at very low concentrations, it exhibits excellent bacteriostatic effects.
Efficacy of Quaternium-73 on Acne
1. Acne Inhibitor
It treats acne by inhibiting Cutibacterium acnes, even at very low concentrations (0.00002%). Its range of action is broad, exhibiting a strong inhibitory effect on Malassezia fungi, thus also having some efficacy against fungal acne.
2. Melanin Inhibitor
At 0.000003%, it inhibits 50% of melanin formation, and completely inhibits melanin formation at 0.07%, superior to kojic acid. It also boasts high safety and cost-effectiveness.
3. Anti-inflammatory
Excessive sebum production due to androgen stimulation; excessive and abnormal keratinization of the hair follicle opening, leading to blockage; blockage of the hair follicle opening creates an anaerobic environment, resulting in the overgrowth of anaerobic Cutibacterium acnes; metabolic products of Cutibacterium acnes induce or exacerbate inflammation, manifesting as papules, pustules, or nodules. Quaternium-73 first inhibits Cutibacterium acnes, simultaneously reducing inflammation, and then unclogs pores, eliminating acne from the root and preventing recurrence.
Quaternium-73 Best-Selling Cases
Quaternium-73 from Berry Medicine
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BERI PHARMA CO., LTD.
Beri Pharma Co., Ltd. is a technology-based enterprise specializing in the research and production of raw materials and preparations for big health (pharmaceuticals, health products), as well as cosmetic raw materials.
Address: No. 2, Nanhua 4th Road, Nanshui Town, Gaolan Port Economic Zone, Zhuhai
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